A highly efficient, one-pot synthesis of α-aminophosphonates over CuO nanopowder

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One-pot synthesis, characterization and of antimicrobial activity of α- aminophosphonates

α-Aminophosphonates (4a-h) were synthesized in one-pot simultaneous reaction of aniline(1), dimethylphosphite(3), and different aromatic aldehydes (2) by Kabachnik–Fields reaction in ethanol at room temperature. The products (4a-h) were obtained in good yields. All these compounds were found to exhibit moderate to good antimicrobial activity.

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ژورنال

عنوان ژورنال: Arkivoc

سال: 2011

ISSN: 1551-7012

DOI: 10.3998/ark.5550190.0012.213